G/S LRRK2 Mouse

Name: FVB/N-Tg(LRRK2*G2019S)1Cjli/J

Strain: 009609

Modification: Transgenic

Description: G/S LRRK2 mice express the mutant form of human leucine rich repeat kinase 2 (LRRK2*G2019S) under the control of the human LRRK2 promoter/enhancer regions on the BAC transgene. Mice show no change in behavior or motor skills.

Application: Mouse model useful for studying Parkinson’s disease via LRRK2*G2019S expression.

Availability: Available from JAX with license from WCM.

*Availability and licensing conditions are subject to change.