hPSC-Derived Lung and Colon Organoids

Principal Investigator: 

Shuibing Chen, Professor of Chemical Biology in Surgery

Tissue: Lung, Colon

Disease: Normal

Species: Human

Modifications: None

Description: Lung and colon organoid models generated using human pluripotent stem cells (hPSCs) which recapitulate relevant
organ biology. The hPSC-derived lung organoids express ACE2, are permissive to SARS-CoV-2 infection, and phenocopy COVID-
19 disease. The organoids may be used in vitro or implanted into immunodeficient mice to generate in vivo xenograft models and are compatible with high-throughput screening. 

Availability: Available by license from WCM.

*Availability and licensing conditions are subject to change.

Intellectual Property

Cornell Reference

  • D-9438, D-9421

Contact Information

Iris Bica

For additional information please contact

Iris Bica
Business Development and Licensing Associate
Phone: (646) 962-5966
Email: ib342@cornell.edu