Chenjian Li
Name: NTac:SD-Tg(SNCA*E46K)70CJLi
Strain: 10679
Modification: Transgenic
Description: These rats contain a human SNCA gene with the E46K mutation, which is liked to familial Parkinson's Disease. Rats demonstrate accumulation and aggregation of α-synuclein in nigral dopamine neurons, decreased dopamine metabolites in the striatum, and oxidative stress – characteristic of early-stage PD.
Application: Basic research and drug development for Parkinson’s Disease.
Availability: Available from Taconic with license from WCM.
*Availability and licensing conditions are subject to change.
Publications
Intellectual Property
Cornell Reference
- D-5203
Contact Information
For additional information please contact
Iris Bica
Business Development and Licensing Associate
Phone: (646) 962-5966
Email: ib342@cornell.edu