Li Gan, Burton P. and Judith B. Resnick Distinguished Professor in Neurodegenerative Diseases and Professor of Neuroscience
Name: C57BL/6J-Apoeem1(APOE3)Lgn
Strain: N/A
Modification: Knock-in
Description: Human APOE3 knock-in mice were generated by inserting a cDNA encoding human APOE3 and a polyA sequence into the endogenous mouse Apoe locus immediately upstream of the start codon via homology-directed repair. This insertion places human APOE3 expression under control of the endogenous mouse Apoe promoter while inactivating the mouse Apoe gene.
Application: Mouse model useful in studying Alzheimer’s Disease.
Availability: Available from WCM.
*Availability and licensing conditions are subject to change.
Publications
Intellectual Property
Cornell Reference
- 11259
Contact Information
For additional information please contact
Ivan Gando
Business Development and Licensing Associate
Phone: (646) 814-6459
Email: ivan.gando@cornell.edu