Lukas Dow, Professor of Biochemistry in Medicine
Name: B6.Cg-Col1a1tm1(tetO-cas9*)Ldow/Mmjax
Strain: 069789-JAX
Modification: Knock-In
Description: IBE knock-in mice express a cytosine base editor (C:G to T:A) under the control of a tetO promoter. This strain provides cytosine base editing to create cancer-related single nucleotide variants (SNVs).
Application: Mouse strain useful in creating individual or multiple SNVs in pancreatic, lung, and intestinal organoids and somatic cells for cancer models.
Availability: Available from JAX with license from WCM.
*Availability and licensing conditions are subject to change.
Intellectual Property
Cornell Reference
- D-10533
Contact Information
For additional information please contact
Iris Bica
Business Development and Licensing Associate
Phone: (646) 962-5966
Email: ib342@cornell.edu