LRRK2(R1441G)Mouse

Principal Investigator: 

Chenjian Li

Name: FVB/N-Khdrbs2Tg(LRRK2*R1441G)135Cjli/J

Strain: 009604

Modification: Transgenic

Description: LRRK2R1441G transgenic mice express the mutant form of human leucine-rich repeat kinase 2 (LRRK2*R1441G) under the control of the human LRRK2 promoter/enhancer regions on the BAC transgene. These mice exhibit multiple late-onset and progressive features of Parkinson’s disease.

Application: Mouse model for studying Parkinson’s disease pathogenesis and neurodegeneration by LRRK2R1441G expression.

Availability: Available from JAX with license from WCM.

*Availability and licensing conditions are subject to change.

Intellectual Property

Cornell Reference

  • D-4184

Contact Information

Iris Bica

For additional information please contact

Iris Bica
Business Development and Licensing Associate
Phone: (646) 962-5966
Email: ib342@cornell.edu