Principal Investigator:
Carl Nathan, Chair of Microbiology and Immunology
Name: B6(Cg)-Grntm1.1Aidi/J
Strain: 013175
Modification: Knock-out
Description: PGRN knock-out mice have exons 1-4 deleted from the granulin locus (Grn). These mice exhibit frontotemporal dementia-like behavior and neuropathology as well as a dysregulated inflammatory response.
Application: Mouse model useful in studying frontotemporal dementia.
Availability: Available from JAX with license from WCM.
*Availability and licensing conditions are subject to change.
Publications
Intellectual Property
Cornell Reference
- D-4866
Contact Information
For additional information please contact
Iris Bica
Business Development and Licensing Associate
Phone: (646) 962-5966
Email: ib342@cornell.edu