R26(F133V)Mouse

Principal Investigator: 

Christopher Barbieri, Peter M. Sacerdote Distinguished Associate Professor in Urologic Oncology

Name: B6.Cg-Gt(ROSA)26Sortm1(SPOP*F133V)Mrbn/J

Strain: 030102

Modification: Targeted mutation

Description: R26F133V mice contain a loxP-flanked STOP sequence upstream of a mutated human speckle-type POZ protein (SPOP) gene. When bred to mice that express Cre recombinase under the control of a promoter of interest, SPOP-F133V is expressed with genomic alterations characteristic of prostate cancer.

Application: Mouse model useful in studying prostate cancer.

Availability: Available from JAX with license from WCM.

*Availability and licensing conditions are subject to change.

Intellectual Property

Cornell Reference

  •  D-7593

Contact Information

Iris Bica

For additional information please contact

Iris Bica
Business Development and Licensing Associate
Phone: (646) 962-5966
Email: ib342@cornell.edu