Christopher Barbieri, Peter M. Sacerdote Distinguished Associate Professor in Urologic Oncology
Name: B6.Cg-Gt(ROSA)26Sortm1(SPOP*F133V)Mrbn/J
Strain: 030102
Modification: Targeted mutation
Description: R26F133V mice contain a loxP-flanked STOP sequence upstream of a mutated human speckle-type POZ protein (SPOP) gene. When bred to mice that express Cre recombinase under the control of a promoter of interest, SPOP-F133V is expressed with genomic alterations characteristic of prostate cancer.
Application: Mouse model useful in studying prostate cancer.
Availability: Available from JAX with license from WCM.
*Availability and licensing conditions are subject to change.
Publications
Intellectual Property
Cornell Reference
- D-7593
Contact Information

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