Method of Differentiation from Human Pluripotent Stem Cells to Monohormonal Cells

Benefits

• Monohormonal β-cell transplant would have the ability to cure the disease, compared to current treatments which solely supplement insulin and insulin production.
• The invention allows almost homogenous preparations of monohormonal cells compared to previous differentiation methods.

Potential Applications

• Transplant of monohormonal cells into the pancreas of diabetes patients to secrete insulin.
• Drug screening platform to identify candidates to treat diabetes.