The Charlson Comorbidity Index: A System for Identifying Patients with High Future Healthcare Costs

Principal Investigator: 

Mary E. Charlson, William T. Foley Distinguished Professor of Medicine

Background & Unmet Need

  • Health costs in the U.S. have been rising significantly, at a pace that is unsustainable
  • To have the best chance of reducing costs, interventions must target those patients who are most likely to incur future high costs
  • Previous work by the Congressional Budget Office determine that multiple chronic conditions was the best predictor of sustained high costs
  • However, there is no consensus about the criteria to define multiple chronic diseases and the definition varies considerably between studies
  • Unmet Need: Method to define and categorize patients with multiple comorbidities to improve predictions of high healthcare cost producers

Technology Overview

  • The Technology: Application of the Charlson Comorbidity Index (CCI) to identify patients who will incur high future healthcare costs
  • The CCI was originally developed to predict survival, and is a measure of aggregate chronic disease burden
  • Here, the CCI was used to predict health costs in the subsequent year, performing as well as prior cost and Diagnostic Cost Group (DCG) in identifying patients in the top 5% or 10%
  • As the comorbidity index increased, total yearly costs increased significantly (P<.001)
  • The CCI may therefore be used prospectively to identify patients who are likely to incur high costs, and aid in the development of cost mitigation strategies

Technology Applications

  • Predicts and identifies patients who will incur high future healthcare costs and high futures rates of hospitalization
  • Enables optimal healthcare resource management to control costs

Technology Advantages

  • Demonstrated ability to predict high healthcare utilizers
  • Allows healthcare systems to intervene early to help patients better manage chronic conditions

The Charlson Comorbidity Index correlates with increasing healthcare costs and is a strong predictor of future healthcare utilization.

Intellectual Property

Patents

  • US Patent Application: US20220215910A1. "System and methods for managing healthcare resources." Published Jul 28, 2022.

Cornell Reference

  • 6867

Contact Information

Brian Kelly, Ph.D.

For additional information please contact

Brian Kelly
Director, Business Development and Licensing
Phone: (646) 962-7041
Email: bjk44@cornell.edu