Principal Investigator:
Mary E. Charlson, William T. Foley Distinguished Professor of Medicine
Background & Unmet Need
- Health costs in the U.S. have been rising significantly, at a pace that is unsustainable
- To have the best chance of reducing costs, interventions must target those patients who are most likely to incur future high costs
- Previous work by the Congressional Budget Office determine that multiple chronic conditions was the best predictor of sustained high costs
- However, there is no consensus about the criteria to define multiple chronic diseases and the definition varies considerably between studies
- Unmet Need: Method to define and categorize patients with multiple comorbidities to improve predictions of high healthcare cost producers
Technology Overview
- The Technology: Application of the Charlson Comorbidity Index (CCI) to identify patients who will incur high future healthcare costs
- The CCI was originally developed to predict survival, and is a measure of aggregate chronic disease burden
- Here, the CCI was used to predict health costs in the subsequent year, performing as well as prior cost and Diagnostic Cost Group (DCG) in identifying patients in the top 5% or 10%
- As the comorbidity index increased, total yearly costs increased significantly (P<.001)
- The CCI may therefore be used prospectively to identify patients who are likely to incur high costs, and aid in the development of cost mitigation strategies
Technology Applications
- Predicts and identifies patients who will incur high future healthcare costs and high futures rates of hospitalization
- Enables optimal healthcare resource management to control costs
Technology Advantages
- Demonstrated ability to predict high healthcare utilizers
- Allows healthcare systems to intervene early to help patients better manage chronic conditions
Publications
Resources
Intellectual Property
Patents
- US Patent Application: US20220215910A1. "System and methods for managing healthcare resources." Published Jul 28, 2022.
Cornell Reference
- 6867
Contact Information

For additional information please contact
Brian Kelly
Director, Business Development and Licensing
Phone: (646) 962-7041
Email: bjk44@cornell.edu